| 9 Jan 2024 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 7,818 | $19.78 | $154,640 9 Jan 2024 | 2,268,363 | ↗ |
| 5 Jan 2024 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 17,483 | $19.43 | $339,695 5 Jan 2024 | 2,276,181 | ↗ |
| 21 Aug 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 2,309 | $22.59 | $52,160 21 Aug 2023 | 2,242,604 | ↗ |
| 10 Aug 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Option | 2,526 | $0.68 | $1,718 10 Aug 2023 | 2,242,439 | ↗ |
| 16 Jun 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Option | 50,000 | $0.68 | $34,000 16 Jun 2023 | 2,289,913 | ↗ |
| 20 Apr 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Option | 25,000 | $0.68 | $17,000 20 Apr 2023 | 2,264,713 | ↗ |
| 13 Feb 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 33,815 | $30.08 | $1,017,155 13 Feb 2023 | 2,239,913 | ↗ |
| 9 Feb 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 28,433 | $29.28 | $832,518 9 Feb 2023 | 2,229,031 | ↗ |
| 5 Jan 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 4,800 | $28.44 | $136,512 5 Jan 2023 | 2,223,664 | ↗ |
| 3 Jan 2023 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 5,029 | $28.73 | $144,483 3 Jan 2023 | 2,213,464 | ↗ |
| 19 Aug 2022 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 2,404 | $33.22 | $79,861 19 Aug 2022 | 2,202,993 | ↗ |
| 11 Feb 2022 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 9,491 | $34.72 | $329,528 11 Feb 2022 | 2,129,648 | ↗ |
| 9 Feb 2022 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Option | 70,749 | $5.65 | $399,732 9 Feb 2022 | 260,640 | ↗ |
| 5 Jan 2022 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 5,007 | $44.78 | $224,213 5 Jan 2022 | 2,113,361 | ↗ |
| 1 Dec 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $44.92 | $823,518 1 Dec 2021 | 2,103,368 | ↗ |
| 1 Nov 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $49.76 | $912,250 1 Nov 2021 | 2,121,701 | ↗ |
| 1 Oct 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $50.38 | $923,617 1 Oct 2021 | 2,140,034 | ↗ |
| 1 Sep 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $54.66 | $1,002,082 1 Sep 2021 | 2,158,367 | ↗ |
| 19 Aug 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 2,376 | $49.57 | $117,778 19 Aug 2021 | 2,176,700 | ↗ |
| 2 Aug 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $51.41 | $942,500 2 Aug 2021 | 2,174,076 | ↗ |
| 1 Jul 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $77.25 | $1,416,224 1 Jul 2021 | 2,192,409 | ↗ |
| 1 Jun 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $61.40 | $1,125,646 1 Jun 2021 | 2,210,742 | ↗ |
| 3 May 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $58.64 | $1,075,047 3 May 2021 | 2,229,075 | ↗ |
| 1 Apr 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $56.60 | $1,037,704 1 Apr 2021 | 2,247,408 | ↗ |
| 1 Mar 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $66.35 | $1,216,461 1 Mar 2021 | 2,305,742 | ↗ |
| 11 Feb 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 9,473 | $70.30 | $665,952 11 Feb 2021 | 2,324,076 | ↗ |
| 8 Feb 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Option | 14,316 | $76.96 | $1,101,759 8 Feb 2021 | 2,318,965 | ↗ |
| 1 Feb 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $68.44 | $1,254,779 1 Feb 2021 | 2,304,649 | ↗ |
| 4 Jan 2021 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 88,334 | $74.96 | $6,621,517 4 Jan 2021 | 2,322,978 | ↗ |
| 30 Mar 2020 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 4,807 | $19.48 | $93,640 30 Mar 2020 | 22,013 | ↗ |
| 3 Dec 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 21,268 | $18.00 | $382,824 3 Dec 2019 | 2,429,304 | ↗ |
| 22 Nov 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 43,485 | $18.02 | $783,600 22 Nov 2019 | 2,450,572 | ↗ |
| 3 Sep 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 8,581 | $18.05 | $154,887 3 Sep 2019 | 2,494,057 | ↗ |
| 3 Jun 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $19.07 | $349,610 3 Jun 2019 | 2,560,971 | ↗ |
| 14 May 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $20.76 | $380,593 14 May 2019 | 2,502,638 | ↗ |
| 1 May 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $24.20 | $443,683 1 May 2019 | 2,579,304 | ↗ |
| 1 Apr 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $25.03 | $458,875 1 Apr 2019 | 2,597,638 | ↗ |
| 1 Mar 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $22.18 | $406,626 1 Mar 2019 | 2,615,971 | ↗ |
| 1 Feb 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $18.72 | $343,212 1 Feb 2019 | 2,634,304 | ↗ |
| 2 Jan 2019 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $19.43 | $356,210 2 Jan 2019 | 2,652,638 | ↗ |
| 27 Nov 2018 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $18.43 | $337,877 27 Nov 2018 | 2,670,971 | ↗ |
| 13 Nov 2018 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $18.09 | $331,662 13 Nov 2018 | 2,729,304 | ↗ |
| 1 Oct 2018 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $21.72 | $398,193 1 Oct 2018 | 2,747,638 | ↗ |
| 4 Sep 2018 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,333 | $19.06 | $349,427 4 Sep 2018 | 2,765,971 | ↗ |
| 29 Aug 2018 | DNLI Denali Therapeutics Inc | Ryan J. Watts President and CEO | Sale | 18,334 | $18.05 | $330,929 29 Aug 2018 | 2,784,304 | ↗ |
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